Effect of three enteral diets with different protein contents on protein metabolism in critically ill infants: a randomized controlled trial.

Introduction: The optimal intake to improve protein metabolism without producing adverse effects in seriously ill infants has yet to be established. The aim of our study was to analyse whether an increased protein intake delivered through enteral nutrition would be associated with an improvement in nitrogen balance and serum protein levels in critically ill infants.

Methods: We conducted a multicentre, prospective randomized controlled trial (December 2016-June 2019).

[Materials for the paediatric resuscitation trolley or backpack: Expert recommendations].

Cardio-respiratory arrest (CPA) is infrequent in children, but it can occur in any place and at any time. This fact means that every health care facility must always have the staff and material ready to resuscitate a child. These recommendations are the consensus of experts of the Spanish Paediatric and Neonatal Resuscitation Group on the material and medication for paediatric and neonatal resuscitation and their distribution and use.

Long-term evolution after in-hospital cardiac arrest in children: Prospective multicenter multinational study.

Objective: The main objective was to study survival and neurologic evolution of children who suffered in-hospital pediatric cardiac arrest (CA). The secondary objective was to analyze the influence of risk factors on the long term outcome after CA.

Methods: prospective, international, observational, multicentric study in 48 hospitals of 12 countries.

Risks in the implementation and use of smart pumps in a pediatric intensive care unit: application of the failure mode and effects analysis.

Objectives: The aim of this study was to identify risk points in the different stages of the smart infusion pump implementation process to prioritize improvement measures.

Methods: Failure modes and effects analysis (FMEA) in the pediatric intensive care unit (PICU) of a General and Teaching Hospital. A multidisciplinary team was comprised of two intensive care pediatricians, two clinical pharmacists and the PICU nurse manager.

Implementation of smart pump technology in a paediatric intensive care unit.

Patient safety is a matter of major concern that involves every health professional. Nowadays, emerging technologies such as smart pumps can diminish medication errors as well as standardise and improve clinical practice with the subsequent benefits for patients. The aim of this paper was to describe the smart pump implementation process in a paediatric intensive care unit (PICU) and to present the most relevant infusion-related programming errors that were prevented.

Preparation of intravenous drug administration guidelines for a pediatric intensive care unit.

Drug administration is one of the main sources of errors in pediatric intensive care units (PICUs). An available guide for intravenous drug administration might be useful. The aim of this article is to present the methodology and results for the development of a guide for intravenous drug administration in a PICU.

Implementing smart pump technology in a pediatric intensive care unit: a cost-effective approach.

Objective: To analyze the cost effectiveness of implementing smart infusion pump technology in a pediatric intensive care unit (PICU).

Material And Methods: An observational, prospective, intervention study with analytical components was carried out. A drug library was developed and integrated into the Carefusion Alaris Guardrails® infusion systems.

Impact of implementing smart infusion pumps in a pediatric intensive care unit.

Purpose: The impact of smart infusion pumps on the interception of errors in the programming of i.v. drug administrations on a pediatric intensive care unit (PICU) is investigated.

Factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study.

Purpose: To analyze prognostic factors associated with in-hospital cardiac arrest (CA) in children.

Methods: A prospective, multicenter, multinational, observational study was performed on pediatric in-hospital CA in 12 countries and included 502 children between 1 month and 18 years. The primary endpoint was survival at hospital discharge.

Hyperoxia, hypocapnia and hypercapnia as outcome factors after cardiac arrest in children.

Purpose: Arterial hyperoxia after resuscitation has been associated with increased mortality in adults. The aim of this study was to test the hypothesis that post-resuscitation hyperoxia and hypocapnia are associated with increased mortality after resuscitation in pediatric patients.

Methods: We performed a prospective observational multicenter hospital-based study including 223 children aged between 1 month and 18 years who achieved return of spontaneous circulation after in-hospital cardiac arrest and for whom arterial blood gas analysis data were available.

Developing a drug library for smart pumps in a pediatric intensive care unit.

Background: The most serious medication errors occur during intravenous administration. The potential consequences are more serious the more critical and younger the patient. Smart pumps can help to prevent infusion-related programming errors, thanks to associated dose-limiting software known as "drug library".

Smart pump alerts: all that glitters is not gold.

Introduction: The implementation of smart pump technology can reduce the incidence of errors in the administration of intravenous drugs. This approach involves developing drug libraries for specific units and setting hard and soft limits for each drug. If a programming error occurs and these limits are exceeded, an alarm sounds and the infusion can be blocked.

[Risk factors for prolonged mechanical ventilation after cardiac surgery in children].

Objective: To study the postoperative factors associated with prolonged mechanical ventilation after cardiac surgery in children.

Design: Prospective observational study.

Setting: Pediatric intensive care unit (PICU).