Publications by authors named "Anfeng Jiang"

Background: Kinase-rearranged spindle cell sarcomas are characterized by unique molecular features. The advent of next-generation sequencing (NGS) has enabled the detection of a multitude of kinase fusions, thereby contributing to the accurate categorization of these tumors.

Case Presentation: A 37-year-old woman experienced the fourth recurrence of a cranial base tumor 25 years following the initial surgery and radiation therapy.

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Article Synopsis
  • Immune cell-enhanced immunotherapy shows promise in improving survival rates in some cancer patients, but many still do not respond due to an immunosuppressive tumor microenvironment (TME).
  • The article highlights the role of stromal interaction molecules 2 (STIM2) as a critical regulator of calcium homeostasis in immune cells, influencing their function through mechanisms like calcium signaling and energy metabolism.
  • The review explores how variations in STIM2 expression and modification within the TME can impact immune responses, proposing STIM2 as a potential therapeutic target to enhance anti-tumor immunity.
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