Publications by authors named "Anfeng Jiang"
Background: Kinase-rearranged spindle cell sarcomas are characterized by unique molecular features. The advent of next-generation sequencing (NGS) has enabled the detection of a multitude of kinase fusions, thereby contributing to the accurate categorization of these tumors.
Case Presentation: A 37-year-old woman experienced the fourth recurrence of a cranial base tumor 25 years following the initial surgery and radiation therapy.
Article Synopsis
- Immune cell-enhanced immunotherapy shows promise in improving survival rates in some cancer patients, but many still do not respond due to an immunosuppressive tumor microenvironment (TME).
- The article highlights the role of stromal interaction molecules 2 (STIM2) as a critical regulator of calcium homeostasis in immune cells, influencing their function through mechanisms like calcium signaling and energy metabolism.
- The review explores how variations in STIM2 expression and modification within the TME can impact immune responses, proposing STIM2 as a potential therapeutic target to enhance anti-tumor immunity.