Investigation of early signs of systolic and diastolic dysfunction among persons with type 1 diabetes.

Background: Persons with type 1 diabetes have a higher risk to develop heart failure than the general population, and the mechanism behind the increased risk is unclear. In epidemiological studies with hospitalisation for heart failure as endpoint HbA1c, body mass index and decreased kidney function are significant risk factors, but it is unclear how these risk factors influence the development of heart failure.

Methods: In this study, we investigated early signs of systolic and diastolic dysfunction with transthoracic echocardiography.