Case report: fatal hepatic failure after aortic valve replacement and sevoflurane exposure.

Purpose: To report a case of lethal hepatotoxicity possibly caused by sevoflurane.

Clinical Features: A 76-yr-old woman with a history of four previous minor surgical procedures developed acute liver failure after general anesthesia with sevoflurane, sufentanil and propofol for aortic valve replacement. After an uneventful procedure the patient was extubated 4.