Publications by authors named "Anett Lindner"
Objective: Insomnia complaints are frequent among kidney transplant (kTx) recipients and are associated with fatigue, depression, lower quality of life and increased morbidity. However, it is not known if subjective insomnia symptoms are associated with objective parameters of sleep architecture. Thus, we analyze the association between sleep macrostructure and EEG activity versus insomnia symptoms among kTx recipients.
View Article and Find Full Text PDFInsomnia and poor self-perceived sleep are very common in patients with chronic kidney disease (CKD). Poor sleep is associated with fatigue, sleepiness, impaired daytime functioning, impaired health-related quality of life, and increased morbidity and mortality. Many illness- and treatment-related factors (metabolic changes, inflammation, altered sleep regulatory mechanisms, symptoms and complications of CKD, comorbid conditions, medications, and renal replacement therapies) may disturb sleep and contribute to the high prevalence of insomnia in this patient population.
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- The study investigates how different lunar phases affect sleep characteristics in humans, given the popular belief that the moon influences behavior and health.
- A total of 319 patients underwent sleep studies, revealing that sleep quality, defined by sleep efficiency and deep sleep duration, was notably worse during the full moon compared to the new moon and alternate moon phases.
- The findings suggest a connection between the full moon and poorer sleep, aligning with previous reports and common beliefs about the lunar cycle's impact on human physiology.
Background: Obstructive sleep apnea (OSA) is often accompanied by the metabolic syndrome. Because both conditions are associated with depressed heart rate variability (HRV) separately, our aim was to study whether co-morbid OSA is associated with more reduced HRV in male patients with the metabolic syndrome.
Methods: In this cross-sectional study, 35 men (age, 57±11 years) with the metabolic syndrome (according to International Diabetes Federation criteria) were included.
Article Synopsis
- A study was conducted with 100 kidney transplant patients to explore the relationship between sleep disorders (obstructive sleep apnea and insomnia) and inflammatory markers.
- Results showed no significant differences in inflammatory markers between patients with or without these sleep disorders, but a higher level of IL-6 was found in insomniacs compared to non-insomniacs.
- The findings suggest that, overall, objectively assessed sleep disorders may not correlate with inflammation in kidney transplant recipients.
Periodic limb movements in sleep (PLMS) is prevalent among dialysed patients and is associated with increased risk of mortality. Our study aimed to determine the prevalence of this disease in a sample of transplanted and waiting-list haemodialysed patients. One hundred transplanted and 50 waiting-list patients underwent polysomnography.
View Article and Find Full Text PDFObjective: Depressive symptoms and the Malnutrition-Inflammation Complex Syndrome (MICS) are prevalent in patients with chronic kidney disease. The complex relationship between MICS and depression has never been studied in kidney transplanted (Tx) patients. Here we evaluate the association between the Malnutrition-Inflammation Score (MIS) (Kalantar score) and depressive symptoms in Tx patients.
View Article and Find Full Text PDFBackground: The combination of chronic malnutrition and inflammation, often termed malnutrition-inflammation complex syndrome or protein-energy wasting, is common in patients with chronic kidney disease. It is associated with increased mortality in patients on maintenance dialysis therapy. We assessed the association of malnutrition-inflammation score (MIS) with all-cause mortality and death-censored transplant loss or death with a functioning transplant in a sample of kidney transplant recipients.
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- Sleep disorders, including restless legs syndrome, are significant chronic issues with notable physiological and psycho-social effects.
- Restless legs syndrome affects 5-10% of the population, yet many health professionals fail to recognize and diagnose it properly, leading to untreated patients.
- This condition not only disrupts sleep, causing insomnia and reduced quality of life, but also impacts daytime functioning and is linked to cardiovascular disorders.
Article Synopsis
- The study examined the prevalence of obstructive sleep apnea (OSA) in kidney transplant patients and those on the waiting list, finding similar rates of OSA in both groups.
- A total of 100 transplant and 50 waiting list patients were assessed through polysomnography, revealing varying levels of OSA severity in both groups.
- OSA was linked to higher body mass index, age, and neck circumference among transplant patients, who also required more antihypertensive medications, indicating a potential connection between OSA and hypertension in kidney transplant recipients.
Restless legs syndrome (RLS) is reportedly associated with depression. This association may be mediated by both sleep-dependent and sleep-independent mechanisms. Here we analyze the association between RLS and depressive symptoms in patients with chronic kidney disease (CKD).
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- RLS (Restless Legs Syndrome) significantly increases the likelihood of insomnia in kidney-transplanted patients, with affected individuals being three times more likely to experience sleep disturbances.
- RLS is independently linked to poorer health-related quality of life across various domains, even after controlling for other factors.
- The study suggests that both sleep-related issues and other factors contribute to the negative impact of RLS on the quality of life in these patients.
Background: Previous studies showed an association between the presence of restless legs syndrome (RLS) and mortality in patients on dialysis therapy. An association between RLS and cardiovascular risk also was reported in the general population. However, no prospective study to date assessed the association between the presence of RLS and mortality in kidney transplant recipients.
View Article and Find Full Text PDFBackground: Obstructive sleep apnoea syndrome (OSAS) is much more prevalent in patients on dialysis than in the general population. Our aim was to assess for the first time the prevalence of patients with a high risk for OSAS and its clinical correlates in a large sample of kidney transplanted patients. We also wanted to compare the prevalence of the disorder between waitlisted dialysis patients (WL) and kidney transplanted patients (Tx).
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