On 3-Coloring of ( )-Free Graphs.

The 3-coloring of hereditary graph classes has been a deeply-researched problem in the last decade. A hereditary graph class is characterized by a (possibly infinite) list of minimal forbidden induced subgraphs ; the graphs in the class are called -free. The complexity of 3-coloring is far from being understood, even for classes defined by a few small forbidden induced subgraphs.

Investigation of Permeation of Theophylline through Skin Using Selected Piperazine-2,5-Diones.

Transdermal administration of drugs that penetrate, in this case directly into the blood circulation, has many advantages and is promising for many drugs thanks to its easy application and good patient compliance. ()-8-Methyl-6,9-diazaspiro[4.5]decan-7,10-dione (alaptide), has been studied as a potential chemical permeation enhancer.

Improvement of Glibenclamide Water Solubility by Nanoparticle Preparation.

Glibenclamide, a drug used for the treatment of type 2 diabetes, belongs to Class II of Biopharmaceutical Classification System. It is a highly permeable, but poorly water-soluble drug. Nanoparticles of glibenclamide were prepared by an emulsion solvent evaporation method using dichloromethane as a solvent of glibenclamide and 3% (w/w) aqueous solution of carboxymethyl dextran sodium salt as a stabilizer, which was found as optimal.