Involvement of the Benzodiazepine Site in the Anticonvulsant Activity of Tapinanthus globiferus against Pentylenetetrazole-induced Seizures in Mice.

is often referred to as an all-purpose herb for the treatment of stroke and epilepsy. The present study investigates the anticonvulsant effect of methanolic leaf extract, active fractions, and lupeol (isolate) of in mice as well as the underlying mechanisms. Following phytochemical studies of , preliminary assays were performed to evaluate MLE-induced toxic effect and behavioral changes.