Analysis of Campylobacter jejuni infection in the gnotobiotic piglet and genome-wide identification of bacterial factors required for infection.

To investigate how Campylobacter jejuni causes the clinical symptoms of diarrhoeal disease in humans, use of a relevant animal model is essential. Such a model should mimic the human disease closely in terms of host physiology, incubation period before onset of disease, clinical signs and a comparable outcome of disease. In this study, we used a gnotobiotic piglet model to study determinants of pathogenicity of C.

Characterisation of proteins extracted from the surface of Salmonella Typhimurium grown under SPI-2-inducing conditions by LC-ESI/MS/MS sequencing.

Salmonella enterica has two pathogenicity islands encoding separate type three secretion systems (T3SS). Proteins secreted through these systems facilitate invasion and survival. After entry, Salmonella reside within a membrane bound vacuole, the Salmonella containing vacuole (SCV), where translocation of a second set of effectors by the Salmonella pathogenicity island 2 (SPI-2) T3SS is initiated.

Social physique anxiety and physical self-esteem: gender and age effects.

The aim of this study was to test the generalisability of the factor pattern, structural parameters, factor correlations and latent mean structure of social physique anxiety and physical self-esteem across gender, age and gender x age. The social physique anxiety scale and general physical self-esteem scale from the physical self-perception profile was administered to high school and university students aged 11-24 years (N = 2334). Confirmatory factor analysis (CFA) was used to test the adequacy of a two-factor correlated model in the full sample, and separately by gender, age and gender x age sub-samples.