Publications by authors named "Andrzej Mrowka"
Article Synopsis
- The study investigates the relationship between advanced glycation end products (AGE) and heart failure in patients with and without type 2 diabetes mellitus (DM2), highlighting their role in cardiac issues.
- Heart samples from 136 patients showed varying levels of AGE accumulation, with higher amounts found in those with DM2 and cardiomyopathy compared to non-diabetic subjects.
- Results indicated that specific staining patterns of AGE in heart tissue can distinguish between conditions of diabetes and heart failure, suggesting that AGE contributes significantly to myocardial complications.
Background: Disturbed glucose metabolism, particularly in diabetes, is an important but not the sole factor leading to advanced glycation end-product (AGE) formation. The AGE amount and its distribution in cardiopathic myocardial tissues in the presence or absence of diabetes are not well documented. The aim of this study was to assess AGE deposition in unaffected myocardial vessels in heart failure patients with and without diabetes mellitus type 2 (DM2) undergoing transplantation.
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