Parathyroid Adenoma Detected in Ga-PSMA PET/CT but Not in the Dedicated Imaging Modalities.

Background: Primary hyperparathyroidism is a common endocrine disorder characterised by excessive parathormone secretion that results in hypercalcemia, primarily caused by parathyroid adenoma. Accurate localisation of hyperfunctioning tissue is essential for curative surgical treatment. Although conventional imaging modalities like ultrasonography and Tc-MIBI scintigraphy (SPECT) along with F-fluorocholine PET/CT are commonly employed, there are cases with false-negative imaging results.

Evaluation of Prostate-Specific Membrane Antigen (PSMA) Immunohistochemical Expression in Early-Stage Breast Cancer Subtypes.

Breast cancer, known for its diverse subtypes, ranks as one of the leading causes of cancer-related deaths. Prostate-specific membrane antigen (PSMA), primarily associated with prostate cancer, has also been identified in breast cancer, though its role remains unclear. This study aimed to evaluate PSMA expression across different subtypes of early-stage breast cancer and investigate its correlation with clinicopathological factors.

Tumour-Induced Osteomalacia-A Long Way to the Diagnosis Facilitated by [Ga]Ga-DOTATATE PET/CT.

Tumour-induced osteomalacia (TIO) is a rare paraneoplastic syndrome. Detecting the primary tumour in TIO is challenging using conventional imaging methods. This study assesses the efficacy of [Ga]Ga-DOTATATE PET/CT in identifying the primary tumour.

Head-to-Head Comparison of [F]PSMA-1007 and [F]FDG PET/CT in Patients with Triple-Negative Breast Cancer.

Background: Triple-negative breast cancer (TNBC) exhibits high aggressiveness and a notably poorer prognosis at advanced stages. Nuclear medicine offers new possibilities, not only for diagnosis but also potentially promising therapeutic strategies. This prospective study explores the potential of prostate-specific membrane antigen (PSMA) as a diagnostic and therapeutic target in TNBC.

Expression of semaphorin 3A (SEMA3A) in breast cancer subtypes.

Breast cancer is a major health concern, and its accurate diagnosis and management depend on identifying its histological type and biological subtype. Semaphorin-3A (SEMA3A) is a membrane protein with diverse roles in cellular processes, including cancer progression and angiogenesis regulation. However, its role in breast cancer remains poorly understood.

Antennnal olfactory and behavioral response of southern pine beetle,Dendroctonus frontalis, to analogs of its aggregation pheromone frontalin.

Antennal olfactory (electroantennogram) and laboratory and field behavioral tests were carried out on the response ofDendroctonus frontalis to its aggregation pheromone frontalin and analogs. The analogs were compounds modified by altering the position and methyl groups and/or by their deletion. Any modification to the frontalin structure significantly reduced both the antennal olfactory and behavioral response byD.