Publications by authors named "Andronikou S"

Purpose: This study examined the occurrence and MRI characteristics of perinatal arterial ischemic stroke (PAIS) in children with cerebral palsy (CP) and suspected term hypoxic-ischemic injury (HII).

Methods: A retrospective review of brain MRI scans was conducted on children with CP and suspected term HII in South Africa.

Results: Out of 1620 children with CP included in the study, 15 (0.

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Article Synopsis
  • Chronic noninfectious osteomyelitis (CNO) is an autoinflammatory bone disorder primarily seen in children and is diagnosed through a combination of clinical, laboratory, and imaging techniques.
  • Whole body magnetic resonance imaging (WBMRI) is the key diagnostic tool, as it helps detect the disease, rule out other conditions like infections and tumors, and assess the extent of bone involvement.
  • Recent advancements in identifying specific patterns on WBMRI enable more accurate and quicker diagnoses, and the imaging is also useful for monitoring treatment response over time.
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Extramedullary hematopoiesis is a phenomenon that occurs in conditions of ineffective bone marrow function. In the context of thalassemias, extramedullary hematopoiesis is more frequently observed in beta-thalassemia intermedia patients, with thoracic paravertebral extramedullary hematopoiesis being relatively common. However, extramedullary hematopoiesis-related pleural effusion is a rare occurrence.

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Purpose: Lung ultrasound (LUS) has been widely used for detecting pneumonia in children. Although LUS offers multiple advantages, its diagnostic accuracy compared to an imaging gold standard, e.g.

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Purpose: The current guidelines for initial cross-sectional imaging in pediatric lymphomas involve computed tomography (CT) of the chest, abdomen, and pelvis. However, whole-body magnetic resonance imaging (MRI) can be favored over CT for diagnosing and staging the disease, given its lack of ionizing radiation and its higher tissue contrast. Imaging characteristics of lymphoid tissue on MRI include a high T2/short tau inversion recovery (STIR) signal.

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Introduction: Lymphobronchial tuberculosis (LBTB) is a tuberculous lymphadenopathy causing airway compression in young children. While it can occur in older children due to factors such as airway size, wall weakness, and immune reconstitutions, severe airway obstruction is more common in younger children.

Methods: Chest X-rays show airway compression, while bronchoscopy is the gold standard for confirming TB-induced airway compression.

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Evaluating lung "volumes" when interpreting pediatric chest radiographs is useful for supporting the diagnosis of lung pathology in children. Lung volumes can be estimated using semi-objective criteria such as anterior rib counting. Estimating lung volumes is one advantage plain radiographs have over other imaging modalities such as ultrasound or even cross-sectional imaging (Computed Tomography and Magnetic Resonance Imaging, where volumes can be calculated, but remain difficult to quickly be appreciated subjectively or semi-objectively in clinical practice).

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Objectives: To investigate the epidemiology, aetiology, diagnostics and management of childhood pneumonia in low and middle income countries (LMICs).

Design: Review of published english literature from 2019 to February 2024.

Results: Lower respiratory tract infections (LRTIs) still result in significant mortality in children under 5 years of age in LMICs.

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Introduction: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic had a significant impact on tuberculosis (TB) control globally, with the number of new TB diagnoses decreasing. Coinfection with some viruses, especially measles, could aggravate TB in children. This is presumably a result of depressed cellular immunity.

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Given the increasing competitiveness of matching into radiology residency programs in the U.S., especially for international medical graduates (IMGs), many IMGs opt to join research fellowships to boost their academic productivity and expand their research portfolios.

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Introduction: Most paediatric upper respiratory infections are virally mediated and result in self-limiting reactive lymphadenopathy. In children younger than 5 years, retropharyngeal lymph nodes may give rise to deep neck space infections in this potential space. Retropharyngeal infections are rare after 5 years because lymph nodes undergo atrophy.

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Background And Purpose: Sturge-Weber syndrome (SWS) is a rare congenital disorder characterized by cortical atrophy and calcifications on late-stage imaging. Understanding the evolution of brain lesions is crucial for effective early interventions, yet the timeline remains unclear. We aimed to evaluate early brain MRI findings and their progression longitudinally on follow-up MRI in children diagnosed with SWS.

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Purpose: Pediatric spinal cord gliomas (PSGs) are rare in children and few reports detail their imaging features. We tested the association of tumoral grade with imaging features and proposed a novel approach to categorize post-contrast enhancement patterns in PSGs.

Methods: This single-center, retrospective study included patients <21 years of age with preoperative spinal MRI and confirmed pathological diagnosis of PSG from 2000-2022.

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Article Synopsis
  • Tuberculous meningitis (TBM) can lead to serious health issues in children and is best diagnosed early using MRI, which can reveal miliary meningeal TB.
  • Two cases are detailed: one is a 9-year-old girl with symptoms like fever and seizures who was found to have TBM through brain MRI and subsequent tests, leading to a four-drug TB treatment.
  • The second case involves a 17-year-old girl with Crohn's disease and persistent ear infections, ultimately diagnosed with TBM, confirmed by various tests including positive cultures for acid-fast bacilli, and treated with a similar four-drug regimen.
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Purpose: The traditional imaging findings reported in Sturge-Weber syndrome (SWS) include endpoints of cortical injury-cortical atrophy and cortical calcifications-but also what has been termed a "leptomeningeal angiomatosis," the latter recognized and reported as a leptomeningeal enhancement on magnetic resonance imaging (MRI). The objective of this study is to demonstrate through neuropathological correlation that the "leptomeningeal angiomatosis" in patients with Sturge-Weber syndrome (SWS), represents a re-opened primitive venous network in the subarachnoid space that likely acts as an alternative venous drainage pathway, seen separately to abnormal pial enhancement.

Materials And Methods: Retrospective review of MR imaging and surgical pathology of patients that underwent surgery for epilepsy at a tertiary, children's hospital.

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Introduction: Tuberculosis (TB) in children under 15 years often results in airway compression, with bronchus intermedius (BI) being the most common site. Endoscopic enucleations can be used to remove lymph nodes and establish an airway in severe cases. Both rigid and flexible bronchoscopy are suitable, with alligator forceps being preferred for its ability to extract tissue.

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Purpose: We aimed to characterize the fetal buccal fat pad (BFP) on magnetic resonance imaging (MRI) to determine the frequency and types of sequences on which the BFP demonstrates low signal intensity and determine any possible correlation with timing of the MRI during fetal development.

Materials And Methods: A retrospective review of all fetal MR studies was performed, and a pediatric radiologist blinded to the referring and final fetal diagnosis as well as outcome evaluated the included cases. A positive buccal fat pad sign (BFS) was recorded as present if a round, symmetric, and bilateral area was seen in the submalar region of the face with the following signal characteristics: T1 hyperintensity, low signal on echo planar imaging (EPI), low signal on true fast imaging with steady-state free precession (TRUFI), and with restriction on diffusion-weighted imaging (DWI).

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  • This study compares the quality of 3-D cranial ultrasound images to traditional 2-D images in neonates, aiming to establish if 3-D could be a viable alternative.
  • Significant findings indicate that 3-D ultrasound identifies more anatomical structures compared to 2-D, particularly in the coronal plane.
  • The results suggest that 3-D ultrasound could be effectively used in neonatal care, especially in remote settings where expert interpretation is needed.
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