Publications by authors named "Andriy Myronenko"

Segmentation is a critical step in analyzing the developing human fetal brain. There have been vast improvements in automatic segmentation methods in the past several years, and the Fetal Brain Tissue Annotation (FeTA) Challenge 2021 helped to establish an excellent standard of fetal brain segmentation. However, FeTA 2021 was a single center study, limiting real-world clinical applicability and acceptance.

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Article Synopsis
  • In-utero fetal MRI is becoming a crucial method for diagnosing and analyzing the developing brain, but manually segmenting cerebral structures is slow and error-prone.
  • The Fetal Tissue Annotation (FeTA) Challenge was established in 2021 to promote the creation of automatic segmentation algorithms, utilizing a dataset with seven segmented fetal brain tissue types.
  • The challenge saw 20 international teams submit algorithms, primarily based on deep learning techniques like U-Nets, with one team's asymmetrical U-Net architecture significantly outperforming others, establishing a benchmark for future segmentation efforts.
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Federated learning (FL) allows the collaborative training of AI models without needing to share raw data. This capability makes it especially interesting for healthcare applications where patient and data privacy is of utmost concern. However, recent works on the inversion of deep neural networks from model gradients raised concerns about the security of FL in preventing the leakage of training data.

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Deep learning (DL) models have provided state-of-the-art performance in various medical imaging benchmarking challenges, including the Brain Tumor Segmentation (BraTS) challenges. However, the task of focal pathology multi-compartment segmentation (e.g.

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The recent outbreak of Coronavirus Disease 2019 (COVID-19) has led to urgent needs for reliable diagnosis and management of SARS-CoV-2 infection. The current guideline is using RT-PCR for testing. As a complimentary tool with diagnostic imaging, chest Computed Tomography (CT) has been shown to be able to reveal visual patterns characteristic for COVID-19, which has definite value at several stages during the disease course.

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Chest CT is emerging as a valuable diagnostic tool for clinical management of COVID-19 associated lung disease. Artificial intelligence (AI) has the potential to aid in rapid evaluation of CT scans for differentiation of COVID-19 findings from other clinical entities. Here we show that a series of deep learning algorithms, trained in a diverse multinational cohort of 1280 patients to localize parietal pleura/lung parenchyma followed by classification of COVID-19 pneumonia, can achieve up to 90.

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Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, application of these models in clinically realistic environments can result in poor generalization and decreased accuracy, mainly due to the domain shift across different hospitals, scanner vendors, imaging protocols, and patient populations etc. Common transfer learning and domain adaptation techniques are proposed to address this bottleneck.

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Purpose: To validate a novel deformable image registration (DIR) method for online adaptation of planning organ-at-risk (OAR) delineations to match daily anatomy during hypo-fractionated RT of abdominal tumors.

Materials And Methods: For 20 liver cancer patients, planning OAR delineations were adapted to daily anatomy using the DIR on corresponding repeat CTs. The DIR's accuracy was evaluated for the entire cohort by comparing adapted and expert-drawn OAR delineations using geometric (Dice Similarity Coefficient (DSC), Modified Hausdorff Distance (MHD) and Mean Surface Error (MSE)) and dosimetric (D and D) measures.

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Purpose: This study investigates the potential application of image-based motion tracking and real-time motion correction to a helical tomotherapy system.

Methods: A kV x-ray imaging system was added to a helical tomotherapy system, mounted 90 degrees offset from the MV treatment beam, and an optical camera system was mounted above the foot of the couch. This experimental system tracks target motion by acquiring an x-ray image every few seconds during gantry rotation.

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Point set registration: coherent point drift.

IEEE Trans Pattern Anal Mach Intell

December 2010

Point set registration is a key component in many computer vision tasks. The goal of point set registration is to assign correspondences between two sets of points and to recover the transformation that maps one point set to the other. Multiple factors, including an unknown nonrigid spatial transformation, large dimensionality of point set, noise, and outliers, make the point set registration a challenging problem.

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Accurate definition of the similarity measure is a key component in image registration. Most commonly used intensity-based similarity measures rely on the assumptions of independence and stationarity of the intensities from pixel to pixel. Such measures cannot capture the complex interactions among the pixel intensities, and often result in less satisfactory registration performances, especially in the presence of spatially-varying intensity distortions.

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Objectives: To compute left ventricular (LV) twist from 3-dimensional (3D) echocardiography.

Background: LV twist is a sensitive index of cardiac performance. Conventional 2-dimensional based methods of computing LV twist are cumbersome and subject to errors.

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Automated motion reconstruction of the left ventricle (LV) from 3D echocardiography provides insight into myocardium architecture and function. Low image quality and artifacts make 3D ultrasound image processing a challenging problem. We introduce a LV tracking method, which combines textural and structural information to overcome the image quality limitations.

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This paper explores the use of deformable mesh for registration of microscopic iris image sequences. The registration, as an effort for stabilizing and rectifying images corrupted by motion artifacts, is a crucial step toward leukocyte tracking and motion characterization for the study of immune systems. The image sequences are characterized by locally nonlinear deformations, where an accurate analytical expression can not be derived through modeling of image formation.

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