Publications by authors named "Andriy Myloserdnyy"
Article Synopsis
- *While peptides often have better safety profiles, they face challenges with pharmacokinetics (PK), limiting their use in medicine.
- *Strategies like glycosylation, combined with other modifications, have been developed to enhance OT's effectiveness, selectivity, and stability in research models.
The molecular underpinnings of organ dysfunction in acute COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function, we performed single-nucleus RNA-seq and spatial transcriptomic profiling of livers from 17 COVID-19 decedents. We identified hepatocytes positive for SARS-CoV-2 RNA with an expression phenotype resembling infected lung epithelial cells.
View Article and Find Full Text PDF