Post-synthesis Oxidation of Superparamagnetic Iron Oxide Nanoparticles to Enhance Magnetic Particle Imaging Performance.

This study investigates the impact of post-synthesis oxidation on the performance of superparamagnetic iron oxide nanoparticles (SPIONs) in magnetic particle imaging (MPI), an emerging technology with applications in diagnostic imaging and theranostics. SPIONs synthesized from iron oleate were subjected to a post-synthesis oxidation treatment with a 1% Oxygen in Argon mixture. MPI performance, gauged via signal intensity and resolution using a MOMENTUM scanner, was correlated to the nanoparticles' physical and magnetic properties.

Magnetic Cellular Backpacks for Spatial Targeting, Imaging, and Immunotherapy.

Adoptive cell transfer (ACT) therapies are growing in popularity due to their ability to interact with diseased tissues in a specific manner. Disc-shaped particles, or "backpacks", that bind to cellular surfaces show promise for augmenting the therapeutic potential of adoptively transferred cells by resisting phagocytosis and locally releasing drugs to maintain cellular activity over time. However, many ACTs suffer from limited tumor infiltration and retention and lack a method for real-time spatial analysis.

Crystal structure and characterization of a new copper(II) chloride dimer with meth-yl(pyridin-2-yl-methyl-idene)amine.

The new copper(II) complex, namely, di-μ-chlorido-bis-{chlorido-[meth-yl(pyri-din-2-yl-methyl-idene)amine-κ ,']copper(II)}, [CuCl(CHN)], (I), with the ligand 2-pyridyl-methyl--methyl-imine (, a product of Schiff base condensation between methyl-amine and 2-pyridine-carbaldehyde) is built of discrete centrosymmetric dimers. The coordination about the Cu ion can be described as distorted square pyramidal. The base of the pyramid consists of two nitro-gen atoms from the bidentate chelate [Cu-N = 2.

Crystal structure of imidazo[1,5-]pyridinium-based hybrid salt (CHN)[MnCl].

A new organic-inorganic hybrid salt [][MnCl] (I) where is the 2-methyl-3-(pyridin-2-yl)imidazo[1,5-]pyridinium cation, is built of discrete organic cations and tetra-chlorido-manganate(II) anions. The cation was formed in the oxidative cyclo-condensation of 2-pyridine-carbaldehyde and CHNH·HCl in methanol. The structure was refined as a two-component twin using (Spek, 2020 ▸) to de-twin the data.

An EPR spin probe study of liposomes from sunflower and soybean phospholipids.

Comparative properties of lecithin-based liposomes prepared from the mixed phospholipids of sunflower seeds, soybean and egg yolk were investigated by electron paramagnetic resonance (EPR) spectroscopy. For these investigations, stable nitroxide radicals, 1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl 5,7-dimethyladamantane-1-carboxylate (DMAC-TEMPO), 5-doxylstearic acid (5-DSA) and 16-doxylstearic acid (16-DSA) were used as spin probes. Binding of the spin probes to the liposome membranes resulted in a substantial increase of the apparent rotational diffusion correlation times.