Publications by authors named "Andrian Wiraguna"

Background: The use of complementary and alternative medicine (CAM) is widespread among patients with chronic disease despite lack of supporting evidence for most CAM types. Concerned regarding higher risk of COVID-19 for HIV-infected patients, probably increase the use of CAM during COVID-19 pandemic in this population. This study aimed to assess the prevalence and factors related to CAM use among HIV-infected patients during COVID-19 pandemic, then identify drug- to-drug interaction (DDI) of antiretroviral (ARV) drugs with CAM that they used.

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Article Synopsis
  • After effective antiretroviral therapy, direct acting antivirals (DAA) can help eliminate HCV in patients co-infected with HIV, but there are obstacles to starting treatment, especially in assessing liver fibrosis.
  • This study evaluated the diagnostic accuracy of APRI and FIB-4 scores for detecting cirrhosis in HIV/HCV co-infected patients, using hepatic transient elastography (TE) as the reference standard.
  • Results showed that APRI and FIB-4 scores had moderate performance in diagnosing cirrhosis, with both tests showing high specificity, which suggests they can be useful alternatives when TE is not accessible.
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