Over the past decades, the problem of bacterial resistance to most antibiotics has become a serious threat to patients' survival. Nevertheless, antibiotics of a novel class have not been approved since the 1980s. The development of antibiotic potentiators is an appealing alternative to the challenging process of searching for new antimicrobials.
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October 2009
The asymmetric unit of the title compound, [Cd(C(30)H(31)N(3)O(6))(2)](PF(6))(2)·3H(2)O, contains one half-cation with the Cd(II) center situated on a twofold rotational axis, one hexa-fluoridophosphate anion and two uncoordinated water mol-ecules, one of which is also situated on a twofold rotational axis. The cations are associated into columns along the a axis through π-π inter-actions between the pyridine and benzene rings, with a centroid-centroid distance of 3.72 (5) Å.
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