Publications by authors named "Andrey N Lavrov"
Article Synopsis
- The role of heat shock proteins (HSPs) in the infection cycle of baculovirus is unclear, despite their known induction in infected cells.
- Researchers noted that HSP70s are associated with baculovirus virions, leading to hypotheses that these chaperones could be involved in virus structure or assembly.
- Experiments with a novel inhibitor (VER-155008) revealed that early addition impeded viral protein synthesis and replication, indicating HSPs are vital early in infection, but mid-replication addition didn’t affect budded virion production, suggesting late assembly stages rely less on these chaperones.
