A Drosophila heart optical coherence microscopy dataset for automatic video segmentation.

The heart of the fruit fly, Drosophila melanogaster, is a particularly suitable model for cardiac studies. Optical coherence microscopy (OCM) captures in vivo cross-sectional videos of the beating Drosophila heart for cardiac function quantification. To analyze those large-size multi-frame OCM recordings, human labelling has been employed, leading to low efficiency and poor reproducibility.

Soliton polarization dynamics in a fiber laser of zero dispersion.

Polarization properties of a soliton generated in a fiber laser of zero dispersion are investigated. Similar to the solitons generated in a fiber laser of all anomalous dispersion, the polarization ellipse of the soliton rotated during pulse evolution inside the cavity. The number of rotations relies on the cavity averaged birefringence with nonlinear bias.

Revaccination in Age-Risk Groups with Sputnik V Is Immunologically Effective and Depends on the Initial Neutralizing SARS-CoV-2 IgG Antibodies Level.

Vaccination against COVID-19 has occurred in Russia for more than two years. According to the Russian official clinical guidelines to maintain tense immunity in the conditions of the ongoing COVID-19 pandemic, it is necessary to use booster immunization six months after primary vaccination or a previous COVID-19 contraction. It is especially important to ensure the maintenance of protective immunity in the elderly, who are at risk of severe courses of COVID-19.

Estimation of anti-orthopoxvirus immunity in Moscow residents and potential risks of spreading Monkeypox virus.

WHO has declared the outbreak of monkeypox as a public health emergency of international concern. In less than three months, monkeypox was detected in more than 30 000 people and spread to more than 80 countries around the world. It is believed that the immunity formed to smallpox vaccine can protect from monkeypox infection with high efficiency.

Investigation of noise-like pulse evolution in normal dispersion fiber lasers mode-locked by nonlinear polarization rotation.

Transition from a gain-guided soliton (GGS) to a fully developed noise-like pulse (NLP) is numerically demonstrated in fiber lasers operated in the normal dispersion regime, which explains well the experimental observation of spectrum evolution that the bottom of the averaged spectrum gradually broadens with pump power increasing. Numerical results suggest that the transition could also happen under the condition of cavity linear phase delay bias change with fixed pump power. It is demonstrated that the peak power clamping effect and the normal dispersion are the key factors leading to the spectrum evolution.

Formation of color solitons and domains in fiber lasers.

Using numerical simulation, we have investigated the generation of color solitons consisting of two radiation fragments with different carrier frequencies in a dual-wavelength laser. The proposed mechanism for the formation of such solitons involves nonlinear losses that increase with increasing intensity, the dispersion of the refractive index, spectral gain inhomogeneity, and the generation of a doublet radiation spectrum, owing to the corresponding spectral-dependent losses in the laser. The proposed theory explains the main features of the experimentally observed formation of color domains in fiber lasers and has the potential for further development of methods for controlling the nonlinear dynamics of laser radiation.

Period doubling eigenstates in a fiber laser mode-locked by nonlinear polarization rotation.

Due to the weak birefringence of single mode fibers, solitons generated in fiber lasers are indeed vector pulses and exhibit periodic parameter change including polarization evolution even when there is a polarizer inside the cavity. Period doubling eigenstates of solitons generated in a fiber laser mode-locked by the nonlinear polarization rotation, i.e.

Narrow-bandwidth h-shaped pulse generation and evolution in a net normal dispersion thulium-doped fiber laser.

We report on experimental generation and evolution of circumstance-susceptible, narrow-bandwidth, h-shaped pulse in a thulium-doped fiber (TDF) laser. With typical mode-locking technique based on nonlinear amplifying loop mirror, a type of h-shaped pulse is generated in a net normal dispersion regime for the first time to our best knowledge. Different from pulses with similar profiles achieved in typical anomalous dispersion regime, the h-shaped pulse here exhibits extremely narrow spectral bandwidth and meanwhile becomes highly circumstance-susceptible.

Generation of noise-like pulses with 203 nm 3-dB bandwidth.

Raman-scattering-assisted noise-like pulse (NLP) generation was achieved by using an appropriate segment of high nonlinearity fiber in an erbium-doped fiber laser. Broadband spectrum with 203 nm 3-dB bandwidth was obtained, which, to the best of our knowledge, is the broadest bandwidth achieved for NLPs. The broadband operation is the result of tailored cavity design, which optimizes various effects including the Raman scattering effect to maximize the bandwidth of NLPs.

Color domains in fiber lasers.

We report on the experimental observation of a color domain (CD) phenomenon in a dissipative soliton fiber laser. The CDs are constituted by a wavelength-dependent condensed phase of pulses in motion. Single CD, dual CD, and tricolor domain that occupy all the cavity space are observed.

Passive harmonic mode locking of soliton crystals.

We report experimental observation of passive harmonic mode locking (HML) in which the basic pattern is a soliton crystal. Several crystal states were generated from an initial large bound state by increasing the pump power. The soliton crystals are identical and progressively span along the cavity to finally take a regular spacing leading to HML of solitons crystal.

Ultrahigh-repetition-rate bound-soliton harmonic passive mode-locked fiber lasers.

On the basis of numerical simulation results, we put forward a way to realize harmonic passive mode locking of fiber lasers with an ultrahigh-repetition-rate pulse train. The equidistant distribution of ultrashort pulses filling the total laser cavity is due to bound-soliton mechanisms. In the case of large bound energy, such long soliton trains are very stable and have the ideal periodic structure as a soliton crystal.

Structural dissipative solitons in passive mode-locked fiber lasers.

On the basis of numerical simulation of fiber laser passive mode locking with anomalous dispersion we have found the dissipative solitons with powerful pedestals having oscillating structure. The pedestal structure causes a complex structural spectrum. These solitons can be multistable: with the same laser parameters the pedestals can have different structures.

Coherent soliton pattern formation in a fiber laser.

We report the observation of bound states of 350 pulses in a ring fiber laser mode locked by nonlinear rotation of the polarization. The phenomenon is described theoretically using a multiscale approach to the gain dynamics; the fast evolution of a small excess of gain is responsible for the stabilization of a periodic pattern, while the slow evolution of the mean value of gain explains the finite length of the quasiperiodic soliton train.