Publications by authors named "Andrey Gordienko"
Aims: This study aimed to investigate the carbohydrate and lipid dynamics, associated inflammation markers and the effectiveness of a grape-derived stilbene concentrate (GDSC) treatment in experimental metabolic syndrome (MetS).
Methods: The study was carried out on 40 male 12-weeks of age Wistar rats. The MetS was induced using the fructose model (feeding with 60%-solid fructose diet for 24 weeks).
Article Synopsis
- The study addresses the ongoing need for affordable and effective localized treatments for rheumatoid arthritis.
- Researchers investigated the effects of Cytos-11, an antisense oligonucleotide, on reducing TNF-α gene expression in a rat model of the disease.
- The treatment with Cytos-11 showed positive results similar to the well-known drug adalimumab (Humira), indicating that antisense technology drugs could be a promising avenue for rheumatoid arthritis therapy.