Publications by authors named "Andrey Bautin"
Coronary artery bypass grafting (CABG) using cardiopulmonary bypass (CPB) causes a systemic inflammatory response that can worsen patient outcomes. Off-pump surgery has been associated with a reduced inflammatory response. The precise mechanisms and the role of extracellular vesicles (EVs) in this context are not fully understood.
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- This study investigated thrombotic and hemorrhagic complications during pregnancy, delivery, and postpartum in women with prosthetic heart valves (PHV), covering 88 pregnancies from January 2011 to December 2022.
- Of the pregnancies, 79 resulted in live births, with higher miscarriage rates in the mechanical valve prosthesis (MVP) group compared to the biological valve prosthesis (BVP) group, alongside notable thrombotic complications predominantly in the MVP group.
- While effective anti-factor Xa activity control was noted to reduce thrombotic events, the study highlighted a concerning rate of postpartum hemorrhagic complications, suggesting a need for revising anticoagulant therapy protocols.
Article Synopsis
- Aortopulmonary window is a rare congenital heart defect leading to severe complications like pulmonary arterial hypertension and heart failure, making pregnancy extremely risky.
- Two case studies are presented involving pregnant women with this defect, one resulting in maternal death postpartum, while the other survived with continued treatment.
- The article emphasizes the importance of specialized care for these patients due to the unique challenges and high risks associated with their condition during pregnancy.
. To evaluate the effect of NO added to the sweep gas of the oxygenator during cardiopulmonary bypass (CPB) on the liver and kidneys in pigs. .
View Article and Find Full Text PDFObjective: To investigate the effect of volatile anesthetics on the rates of postoperative myocardial infarction (MI) and cardiac death after coronary artery bypass graft (CABG).
Design: A post hoc analysis of a randomized trial.
Setting: Cardiac surgical operating rooms.
Objectives: The effect of ischaemic postconditioning (IPost) on postcardioplegic cardiac function is not known. We hypothesized that IPost was cardioprotective in adult patients undergoing elective aortic valve replacement.
Methods: In a multicentre, prospective, randomized trial, patients (n = 209) were randomized to either a standard operation (controls) or postconditioning.
Background: This study compared the hemodynamic effects and gas exchange under several different ventilator settings-with regard to tidal volume, respiratory rate, and end-expiratory pressure-in patients after coronary artery bypass grafting (CABG).
Methods: Prospective interventional cohort study with a controlled group in a single cardiosurgical ICU involving 119 patients following on-pump CABG surgery. During the 1st postoperative hour, the intervention group patients were ventilated with Vt 10 ml × kg, RR 14/min, PEEP 5 cmHO ("conventional ventilation").
Background: Volatile (inhaled) anesthetic agents have cardioprotective effects, which might improve clinical outcomes in patients undergoing coronary-artery bypass grafting (CABG).
Methods: We conducted a pragmatic, multicenter, single-blind, controlled trial at 36 centers in 13 countries. Patients scheduled to undergo elective CABG were randomly assigned to an intraoperative anesthetic regimen that included a volatile anesthetic (desflurane, isoflurane, or sevoflurane) or to total intravenous anesthesia.
This multicenter study investigated the possibility of reducing mortality rate by administering natural lung surfactant additional to standard therapy to treat patients after cardiac surgery who developed an acute respiratory failure (ARDS/ALI).A total of 78 patients (1998-2002) diagnosed with ALI or ARDS were enrolled in the study; patients were considered for study entry only if they developed ALI/ARDS within 72 h after cardiac surgery. A total of 36 patients (2000-2002) received Surfactant-BL via bronchoscope at a dose of 3 mg/kg twice a day, and 42 patients (1998-2000) served as the historical control.
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