Publications by authors named "Andrew van Eck"
Ther Drug Monit
June 2024
Article Synopsis
- Vancomycin is a long-used antibiotic for treating gram-positive infections in hospitals, but its benefits as a loading dose for neonates remain debated.
- The study examined how vancomycin loading doses affect achieving therapeutic targets in neonates with sepsis by comparing data before and after guideline changes in a South African neonatal unit.
- Results showed that neonates receiving loading doses had significantly earlier target attainment, but overall target achievement at 24 hours was similar between both groups, with low rates of kidney toxicity observed.
