Publications by authors named "Andrew Winder"
Bioinformatics
October 2010
Article Synopsis
- DMDM (Domain mapping of disease mutations) is a database that maps disease mutations to specific gene, protein, or domain locations, providing a unique view of human coding mutations on protein domains.
- It utilizes a sequence alignment tool (HMMer) to align human proteins with conserved protein domains, allowing for the identification and functional annotation of disease mutations and polymorphisms.
- The database is accessible for free at http://bioinf.umbc.edu/dmdm and offers insights into molecular relationships among mutations from various diseases, surpassing traditional gene-centric visualization methods.
