Extraction and reduction of parameters from hand-drawn Archimedes spirals for clinical tremor assessment.

Background: Patients' hand-drawn Archimedes spirals are widely used in the neurological community to grade tremors. These spirals are either drawn on paper and Xeroxed/scanned into digital images or digitizing tablets are used for the drawings. This process introduces artifacts such as variable widths of the drawn lines with varying pixel grey scale values.

Uni-Directionally Oriented Fibro-Porous PLLA/Fibrin Bio-Hybrid Scaffold: Mechano-Morphological and Cell Studies.

In this study, we report a biohybrid oriented fibrous scaffold based on nanofibers of poly(l-lactic acid) (PLLA)/fibrin produced by electrospinning and subsequent post-treatment. Induced hydrolytic degradation of the fibers in 0.25 M NaOH solution for various time periods followed by the immobilization of fibrin on the hydrolyzed fiber surfaces was shown to significantly affect the mechanical properties, with the tensile strength (40.