Cerebral metabolism in dogs assessed by (18)F-FDG PET: a pilot study to understand physiological changes in behavioral disorders in dogs.

The positron emission tomography (PET) imaging technique, which is utilized in human behavior and psychiatric disorder research, was performed on the brains of clinically normal mixed breed dogs, 3 hound-type (long floppy ears) mixed breed dogs and 3 non-hound retriever-type mixed breed dogs. Glucose metabolism was obtained with F-18 fluorodeoxyglucose (FDG), and quantitative analysis was performed by standardized uptake value (SUV) measurement. Magnetic resonance (MR) images were obtained in each dog, and these images were superimposed on PET images to identify anatomical locations.

Randomized, controlled clinical trial of the efficacy of fluoxetine for treatment of compulsive disorders in dogs.

Objective: To evaluate efficacy of fluoxetine hydrochloride for treatment of compulsive disorders in dogs.

Design: Randomized, controlled clinical trial.

Animals: 63 dogs with compulsive disorders.

Canine aggression toward familiar people: a new look at an old problem.

Dogs that are aggressive toward their owners have long been regarded as being dominant. This article presents scientific evidence that does not support this claim. Based on this evidence, the authors present an alternative explanation for canine aggression toward owners and outline a treatment plan.

Diagnosis and management of compulsive disorders in dogs and cats.

This article discusses the presenting signs, diagnosis, and differential diagnosis of compulsive disorder. Problems with the diagnosis and heterogeneity of the condition are discussed. Likely causes, development, and pathophysiology of the condition form the basis for the clinical approach to the treatment of the condition.