Incorporation of prior knowledge and habits while solving anagrams.

Games and puzzles provide a valuable context for examining human problemsolving behavior. We recorded and analyzed the sequence of letters viewed by the participants of our study while they were solving anagram puzzles. The goal was to examine and understand how people's linguistic habits and prior knowledge influenced their eye movements.

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis.

Background: Imiquimod (IMQ) produces a cutaneous phenotype in mice frequently studied as an acute model of human psoriasis. Whether this phenotype depends on strain or sex has never been systematically investigated on a large scale. Such effects, however, could lead to conflicts among studies, while further impacting study outcomes and efforts to translate research findings.