Publications by authors named "Andrew Spielman"

Article Synopsis
  • Pierre Fauchard, known as the father of dentistry, made significant contributions to various dental fields, although his impact on oral medicine and maxillofacial pathology was previously overlooked.
  • This study aimed to uncover Fauchard’s work on oral diseases by analyzing both French and English sources, gathering information on diagnosed and treated conditions.
  • The research identified his contributions to diseases like scurvy, abscesses, and oral ulcers, highlighting his importance in diagnosing and treating various oral health issues relevant to modern dentistry.
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History of Dentistry starts from the moment the Late Paleolithic Man used a toothpick fashioned from a bone or wood splinter, or the moment our human ancestors began to manipulate the surface of a tooth to remove its retentiveness, so food does not get stuck. That was at least 14,000 years ago, based on available evidence. The current timeline, compiled in this article, is one of many published over the years.

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This position paper explores the historical transitions and current trends in dental education and practice and attempts to predict the future. Dental education and practice landscape, especially after the COVID-19 epidemic, are at a crossroads. Four fundamental forces are shaping the future: the escalating cost of education, the laicization of dental care, the corporatization of dental care, and technological advances.

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Article Synopsis
  • Repeated exposure to capsaicin leads to reduced sensitivity, known as capsaicin desensitization, which is more pronounced in heavy chili consumers compared to infrequent ones.
  • A study with two groups of healthy volunteers showed significant reductions in reported oral burn after systematic low-dose capsaicin rinses, but no decrease in the expression of the capsaicin receptor (TRPV1) was observed.
  • Other compounds like vanillyl butyl ether and cinnamaldehyde also exhibited reduced burn sensations, suggesting a broader mechanism at play in desensitization beyond just the capsaicin receptor.
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John Greenwood (1760-1819) was George Washington's preferred dentist. He practiced in New York and made at least one of eight sets of dentures Washington wore (currently in the collection of the New York Academy of Medicine (NYAM). We know very little about John Greenwood's (JG) formal education, except that he came from a famous family of dentists.

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If one could be a patient repeatedly, every twenty-five years, starting in 1825, the evolution and comparison of dental care and dental practice would be historically meaningful. Such a as a perpetual patient through 200 years, is the purpose of this paper. The changes that occurred over 200 years provide a sense of the progress in treating patients and the transformation of a painful and dreaded experience to a highly sophisticated painless profession.

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Teaching History of Dentistry and Medicine in dental curricula has declined over the past half century. The cause of this decline is a lack of expertise, time in a crowded curriculum and a decline in interest in the humanities among dental students. The current paper describes a model of teaching History of Dentistry and Medicine at New York University College of Dentistry, a model that could be replicated at other schools.

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If one could attend the same College of Dentistry repeatedly, every twenty years, starting in 1880, the evolution and comparison of student life would be historically meaningful. Such a , as a perpetual dental student through 140 years, is the purpose of this paper. To illustrate this unique perspective, New York College of Dentistry, was chosen.

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Human taste cells are a heterogeneous population of specialized epithelial cells that are constantly generated from progenitor taste cells. Type I and type III taste cells express some neural markers, and studies have reported that direct innervation by neurons is not required for taste cell development. To our knowledge, no previous study has demonstrated that taste cells can differentiate into neuron-like cells or any other non-taste cell type.

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The COVID-19 pandemic caused by SARS-CoV-2 virus quickly spread globally, infecting over half a billion individuals, and killing over 6 million*. One of the more unusual symptoms was patients' complaints of sudden loss of smell and/or taste, a symptom that has become more apparent as the virus mutated into different variants. Anosmia and ageusia, the loss of smell and taste, respectively, seem to be transient for some individuals, but for others persists even after recovery from the infection.

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Teaching history of dentistry and/or medicine in dental schools is not a priority today. A half a century ago it was part of a significant number of dental school curricula. As advances in science occurred and more demand on the curriculum were made, history of medicine and dentistry (HMD) was largely cast aside.

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Quackery in medicine is as old as medicine. In times of crisis desperate patients believe in extraordinary claims. In the annals of pain killer quack medicine, elixirs, nostrums and liniments hold a special position.

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Quackery in medicine is as old as medicine itself. In times of crisis, desperate patients often believe extraordinary claims. In the annals of pain-killer quack medicine, elixirs, nostrums and liniments hold a prominent position.

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Major pandemics have tremendous effects on society. They precipitated the early decline of the Western Roman Empire and helped spread Christianity. There are countless such examples of infectious diseases altering the course of history.

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Quackery in medicine is as old as medicine itself. In times of crisis, desperate patients often believe extraordinary claims. In the annals of pain-killer quack medicine, snake oil, elixirs, nostrums and Indian liniments hold a special position.

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Quackery in medicine is as old as medicine itself. In times of crisis desperate patients often believe extraordinary claims. In the annals of pain killer quack medicine, elixirs, nostrums and liniments hold a special position.

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Zika virus (ZIKV) is an emerging virus belonging to the genus Flavivirus. ZIKV infection is a significant health concern, with increasing numbers of reports of microcephaly cases in fetuses and Guillain-Barré syndrome (GBS) in adults. Interestingly, chemosensory disturbances are also reported as one of the manifestations of GBS.

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Quackery in medicine is as old as medicine. In times of crisis desperate patients believe in extraordinary claims. In the annals of pain killer quack medicine, elixirs, nostrums and liniments hold a preeminent position.

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The aim of this study was to assess the development of personalized dentistry in the curricula of North American dental schools from 2014 to 2017. In 2014, a web-based survey on personalized medicine/dentistry (PM/PD) was distributed to academic deans of all U.S.

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The peripheral taste and olfactory systems in mammals are separate and independent sensory systems. In the current model of chemosensation, gustatory, and olfactory receptors are genetically divergent families expressed in anatomically distinct locations that project to disparate downstream targets. Although information from the 2 sensory systems merges to form the perception of flavor, the first cross talk is thought to occur centrally, in the insular cortex.

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TAS2R38 is a human bitter receptor gene with a common but inactive allele; people homozygous for the inactive form cannot perceive low concentrations of certain bitter compounds. The frequency of the inactive and active forms of this receptor is nearly equal in many human populations, and heterozygotes with 1 copy of the active form and 1 copy of the inactive form have the most common diplotype. However, even though they have the same genotype, heterozygotes differ markedly in their perception of bitterness, perhaps in part because of differences in TAS2R38 mRNA expression.

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Article Synopsis
  • CHRNs (cholinergic receptors) are found in certain human taste cells, specifically HBO cells, and their expression is affected by exposure to nicotine and ethanol, with variations based on dose and duration.* -
  • The study revealed that exposing HBO cells to nicotine or ethanol increases CHRN mRNA and protein expression, while simultaneous exposure to both substances results in a smaller increase than when exposed to either one alone.* -
  • Additionally, CHRNs in HBO cells influence calcium ion levels, and nicotine exposure decreases BDNF levels within these cells while increasing its release into the media, suggesting a role in neuropeptide regulation.*
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Dr. Bernhard Weinberger (1885-1960), an alumnus of the University of Pennsylvania School of Dental Medicine, class of 1910 and a specialist in orthodontics, was a faculty at NYU Dentistry from 1923-1931 as lecturer and later professor in History of Dentistry. Part of his famous collection of rare books ended up at New York University College of Dentistry shortly before his death.

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Using cigarettes and alternative tobacco products (ATPs) is associated with negative oral health outcomes, and dental health professionals are poised to help patients quit. The aim of this study was to determine dental, dental hygiene, and advanced dental students' use, knowledge, and beliefs about cigarettes and ATPs, including perceptions about their education in tobacco dependence treatment and counseling experience. All 1,783 students enrolled in the dental, dental hygiene, and postdoctoral dental programs at the New York University College of Dentistry were invited to participate in the survey in 2016.

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