Clinical and Dosimetric Impact of 2D kV Motion Monitoring and Intervention in Liver Stereotactic Body Radiation Therapy.

Purpose: Positional errors resulting from motion are a principal challenge across all disease sites in radiation therapy. This is particularly pertinent when treating lesions in the liver with stereotactic body radiation therapy (SBRT). To achieve dose escalation and margin reduction for liver SBRT, kV real-time imaging interventions may serve as a potential solution.

A Geometric Model of Ultrasound Backscatter to Describe Microstructural Anisotropy of Tissue.

Methods to assess ultrasound backscatter anisotropy from clinical array transducers have recently been developed. However, they do not provide information about the anisotropy of microstructural features of the specimens. This work develops a simple geometric model, referred to as the , of backscatter coefficient anisotropy.

Gynecologic interstitial brachytherapy curriculum using a low-cost phantom with ultrasound workshop and a treatment planning workshop is effective.

Purpose/objective(s): Standardized simulation training geared towards interstitial brachytherapy (IS BT) for gynecologic malignancies is lacking in radiation oncology resident education. We developed and implemented a curriculum for IS BT training with (1) lecture on equipment, workflow, and guidelines, (2) hands-on ultrasound-guided IS BT workshop, and (3) treatment planning workshop.

Methods And Material: The cost in materials of each phantom was approximately $66.

A framework for developing community-focused medical physics outreach programs.

Purpose: In STEM education and careers, underrepresented minorities (URMs) experience higher attrition than non-URM counterparts. Informal educational experiences, such as outreach, have been identified to increase URM awareness and enrollment in STEM. The objectives of this work were to (1) elucidate the current state of racial and ethnic diversity in medical physics and (2) provide a community-focused framework for building effective outreach programs geared toward K-12 URM students and their families.

Quantitative Ultrasound Detects Smooth Muscle Activity at the Cervical Internal Os in Vitro.

The cervix has two biomechanical functions: to remain closed while the fetus develops throughout pregnancy, and to open for delivery of the fetus at full term. This dual function is principally attributed to collagen within the extracellular matrix (ECM). However, recent evidence suggests that other ECM, and non-ECM, components play a role as well.

Quantitative Ultrasound Parameters Based on the Backscattered Echo Power Signal as Biomarkers of Cervical Remodeling: A Longitudinal Study in the Pregnant Rhesus Macaque.

Clinical prediction and especially prevention of abnormal birth timing, particularly pre-term, is poor. The cervix plays a key role in birth timing; it first serves as a rigid barrier to protect the developing fetus, then becomes the pathway to delivery of that fetus. Imaging biomarkers to define this remodeling process could provide insights to improve prediction of birth timing and elucidate novel targets for preventive therapies.

Quantitative assessment of cervical softening during pregnancy in the Rhesus macaque with shear wave elasticity imaging.

Abnormal parturition, e.g. pre- or post-term birth, is associated with maternal and neonatal morbidity and increased economic burden.

Evaluation of gantry speed on image quality and imaging dose for 4D cone-beam CT acquisition.

Background: This study investigates the effect of gantry speed on 4DCBCT image quality and dose for the Varian On-Board Imager®.

Methods: A thoracic 4DCBCT protocol was designed using a 125 kVp spectrum. Image quality parameters were evaluated for 4DCBCT acquisition using Catphan® phantom with real-time position management™ system for gantry speeds varying between 1.