Publications by authors named "Andrew S Weiss"

Article Synopsis
  • The study investigated the effectiveness of lower doses of rabbit antithymocyte globulin (rATG) as an induction agent in kidney transplant patients at high risk of acute rejection.
  • The analysis included 83 kidney transplant recipients who were given either 3 or 4 doses of rATG (1.5 mg/kg) and showed low rejection rates (10% for 3 doses and 11% for 4 doses) along with 100% patient and graft survival at one year.
  • Results indicated that the 3-dose group had a significantly shorter hospital stay, suggesting that lower exposure to rATG could still provide effective protection against rejection while reducing hospital costs.
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Background: Organ donor characteristics can be used to predict outcomes in kidney transplantation. We hypothesized that pancreas donation status could reflect organ quality and be predictive of kidney graft outcomes following Standard Criteria Donor (SCD) kidney transplantation.

Methods: We performed a retrospective analysis of deceased donor kidney alone (DD KA) transplants reported to SRTR from 1992 to 2005.

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Background: Simultaneous pancreas-kidney transplantation (SPK) may provide superior patient and kidney graft survival compared with deceased donor kidney transplant alone (DD KA), not because of the addition of a pancreas transplant but because of differences in organ donor, recipient, and transplant characteristics.

Methods: We performed a retrospective analysis from the scientific registry of transplant recipients database comparing patient and kidney graft survival of SPK and DD KA recipients from 1997 to 2005, segregating the DD KA recipients into (a) recipients of KA from pancreas donors (KA, P+) and (b) recipients of KA from non-pancreas donors to control for donor differences.

Results: Of 8453 SPK waitlisted patients, 7952 received SPK, 101 received KA, P+, and 401 received KA from non-pancreas donors (KA, P-).

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Background And Objectives: Simultaneous pancreas-kidney transplantation (SPK) is regarded as the treatment of choice for type 1 diabetes (T1DM) and kidney dysfunction, despite the morbidity associated with pancreas transplantation. These morbidities often influence selection of SPK versus living-donor kidney alone (LD KA) transplant. This study quantifies the impact of pancreas graft function on outcomes following SPK.

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Background And Objectives: BK virus-associated nephropathy (BKVAN) has emerged as a leading cause of kidney graft loss, with no known predictors for graft loss and no consensus regarding treatment other than reduction of immunosuppression.

Design, Setting, Participants And Measurements: A single-center retrospective analysis was performed of all cases of BKVAN from 1999 to 2005 for clinical predictors of graft loss, with evaluation of the impact of immunosuppression withdrawal (3-drug to 2-drug immunosuppression) within the first month versus reduction of immunosuppression.

Results: Of 910 kidney transplants, 35 (3.

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Background: A 61-year-old female with end-stage renal disease who was undergoing hemodialysis presented with an 8-week history of upper and lower extremity weakness associated with skin tightness and contractures.

Investigations: Physical examination, blood analysis, electromyogram and skin biopsy.

Diagnosis: Nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis.

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Background: Medical management is the conventional treatment for Stanford Type B aortic dissections as surgery is associated with significant morbidity and mortality. The advent of endovascular interventional techniques has revived interest in treating end-organ complications of Type B aortic dissection. We describe a patient who benefited from endovascular repair of renal artery stenosis caused by a dissection flap, which resulted in reversal of his end-stage renal disease (ESRD).

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