Publications by authors named "Andrew S Cross"

Article Synopsis
  • * A total of 294 patients were analyzed, with 120 receiving the combination of PAIs and CACBs, while 174 received only PAIs.
  • * Results showed that adding CACBs significantly reduced early narcotic use without negatively impacting pain levels, knee range of motion, or hospital stay duration.
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LPS treatment of macrophages induces TG accumulation, which is accentuated by TG-rich lipoproteins or FFA. We defined pathways altered during macrophage activation that contribute to TG accumulation. Glucose uptake increased with activation, accompanied by increased GLUT1.

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Angiopoietin like protein 4 (ANGPTL4) inhibits lipoprotein lipase (LPL) activity. Previous studies have shown that Toll-like Receptor (TLR) activation increases serum levels of ANGPTL4 and expression of ANGPTL4 in liver, heart, muscle, and adipose tissue in mice. ANGPTL4 is expressed in macrophages and is induced by inflammatory saturated fatty acids.

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