Factors Predicting Operative Difficulty of Laparoscopic Total Mesorectal Excision.

Background: Laparoscopic total mesorectal excision is a challenging procedure requiring high-quality surgery for optimal outcomes. Patient, tumor, and pelvic factors are believed to determine difficulty, but previous studies were limited to postoperative data.

Objective: This study aimed to report factors predicting laparoscopic total mesorectal excision performance by using objective intraoperative assessment.

Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery.

Background And Objectives: Combining laparoscopy and enhanced recovery provides benefit to short-term outcomes after colorectal surgery. Advances in training and techniques have allowed surgeons to operate on cases that are technically challenging and associated with prolonged operative time. Laparoscopic techniques improve the outcome of enhanced recovery after colorectal surgery; however, there are no specifications on the effect of prolonged operations on the outcome.

The angiographic anatomy of the small arteries and their collaterals in colorectal resections: some insights into anastomotic perfusion.

Objective: The aim of this study was to examine by screening angiography the anatomy of the small arteries and their collaterals in colorectal resections in order to identify factors that might be implicated in anastomotic leak.

Summary Background Data: Anastomotic leak is more frequent following low anterior resection. Vascular compromise is frequently implicated but poorly understood as a mechanism.

The insulin-like growth factor type 1 receptor and colorectal neoplasia: insights into invasion.

This study examines the expression of the insulin-like growth factor type 1 receptor (IGF-1R) in colorectal neoplasia. Previous studies have shown that the IGF-1R is expressed at high levels in normal embryonic stem cells and in many cancer phenotypes. However, lower IGF-1R levels are expressed in some advanced cancer phenotypes.