Publications by authors named "Andrew R Vince"

We evaluated the extent of hepatic fibrosis in chronic liver disease of dogs using a modification of Ishak's staging criteria for human chronic liver disease, and examined the association of stage of fibrosis with immunophenotypic markers of transdifferentiation of hepatic sinusoidal endothelial cells and hepatic stellate cells. Formalin-fixed, paraffin-embedded, hematoxylin and eosin-stained liver biopsy specimens from 45 case dogs with chronic liver disease and 55 healthy control dogs were scored for the presence and extent of fibrosis. This stage score for fibrosis strongly correlated with upregulated von Willebrand factor (vWF) expression in lobular sinusoidal endothelial cells (Spearman correlation coefficient [SCC] = 0.

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A 22-month-old indoor/outdoor neutered male domestic short-haired cat had a history of progressive lethargy, vomiting, and decreased appetite. Abdominal ultrasound revealed an irregular hyperechoic mass in the mid-abdomen. He was unresponsive to symptomatic medical management and was euthanized after 3 days of hospitalization.

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Article Synopsis
  • - A young rough-coated collie dog showed serious health issues, including neurological problems, blindness, and severe diarrhea, due to a disseminated algal infection.
  • - The infection was caused by Prototheca zopfii, which was found in the dog's feces, urine, and blood samples.
  • - During the necropsy, granulomas with these organisms were discovered in crucial body parts like the colon, heart, kidneys, and eyes.
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A 7-year-old, bichon frise dog was incidentally diagnosed with cecal impaction. Typhlectomy was performed as cecal rupture and resultant septic peritonitis appeared to be imminent. Histopathological evaluation did not identify an underlying cause for impaction and cecal dysmotility was suspected.

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Necrotic enteritis (NE) is one of the most important enteric diseases in poultry and is a high cost to the industry worldwide. It is caused by avian-specific, Necrotic Enteritis Beta toxin (NetB)-producing, strains of Clostridium perfringens that also possess in common other virulence-associated genes. In Europe the disease incidence has increased since the ban on in-feed "growth promoting" antibiotics.

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Objective: To describe the clinical features, diagnostic work-up, treatment, and outcome of a dog with oral thermal injury secondary to chewing on a salbutamol metered-dose inhaler (MDI).

Case Summary: A Boxer dog was presented after chewing on a salbutamol MDI. The dog was anxious, tachycardic and had moderate hypokalemia.

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Multilobular osteochondrosarcoma (MLO) of the os penis was diagnosed in a dysuric dog. Recurrence was confirmed or suspected twice over a 22-month period. This is the first reported case of MLO occurring in the os penis, and the 5th reported case of neoplasia of the os penis in the dog.

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