Effects of reported beta-lactam allergies on pneumonia outcomes in lung transplant recipients.

Background: The effects of reported beta-lactam allergies on clinical outcomes have been understudied in lung transplant recipients. We evaluated reported beta-lactam allergies on clinical outcomes in this population.

Methods: A single-center retrospective cohort analysis was performed.

Impact of donor multidrug-resistant organisms on solid organ transplant recipient outcomes.

Background: The impact of donor colonization or infection with multidrug-resistant organisms (MDROs) on solid organ transplant (SOT) recipient outcomes remains uncertain. We thus evaluated the association between donor MDROs and risk of posttransplant infection, graft failure, and mortality.

Methods: A multicenter retrospective cohort study was performed.

Functional and phylogenetic characterization of noncanonical vitamin B-binding proteins in zebrafish suggests involvement in cobalamin transport.

In humans, transport of food-derived cobalamin (vitamin B) from the digestive system into the bloodstream involves three paralogous proteins: transcobalamin (TC), haptocorrin (HC), and intrinsic factor (IF). Each of these proteins contains two domains, an α-domain and a β-domain, which together form a cleft in which cobalamin binds. Zebrafish () are thought to possess only a single cobalamin transport protein, referred to as Tcn2, which is a transcobalamin homolog.