Publications by authors named "Andrew Pitkin"

Article Synopsis
  • * The overall one-year mortality rate for the cohort was 9%, with different operative mortality rates and outcomes observed across the three pathways: standard risk (2.6%), high-risk noncardiac (10%), and high-risk cardiac with advanced support.
  • * The findings suggest that a tailored management approach can lead to favorable outcomes, particularly in high-risk patients, with a considerable number successfully undergoing cardiac transplantation and surviving beyond one year.
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  • Various surgical methods to treat aortic coarctation in neonates and infants are evaluated based on patient anatomy, with a review conducted on 132 patients at the University of Florida from 2006 to 2021.
  • Patients underwent surgery either for aortic coarctation or hypoplastic aortic arch, with techniques varying between median sternotomy and left lateral thoracotomy, where the most common methods included end-to-side reconstruction and extended end-to-end repair.
  • The study found a 0.76% operative mortality rate and a low incidence of recurrent coarctation requiring further operations, indicating that personalized surgical approaches are effective and safe.
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  • The study evaluated the outcomes of 36 infants weighing less than 5 kg who received a Berlin Heart pulsatile ventricular assist device, comparing those with acquired heart disease (8 patients) and congenital heart disease (28 patients).
  • The primary focus was on mortality and survival rates, which showed a 1-year survival estimate of 62.7% for all patients and 87.5% specifically for those with acquired heart disease.
  • Notably, 72.22% of the infants were successfully bridged to transplantation, with a significant difference in success rates between those with acquired (100%) and congenital heart disease (64.3%).
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Objective: This study quantifies the change in intraocular pressure (IOP) secondary to wearing neck seals in scuba diving drysuits. Previous work demonstrates significant pressures exerted by these seals; we hypothesize that they would.

Methods: IOP was measured in 33 divers before and while wearing a drysuit using rebound tonometry.

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Article Synopsis
  • * Key findings revealed that 1-year survival rates were significantly lower for CHD patients (59.9%) compared to AHD patients (88.6%), and this trend continued at 5 years (55.4% for CHD vs. 85.3% for AHD).
  • * The duration of VAD support varied, with CHD patients receiving median support for 134 days and AHD patients for 97 days; additionally, the outcomes showed that a majority of both groups went on
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Article Synopsis
  • Some patients with functionally univentricular circulation face severe cardiac failure and may require a ventricular assist device (VAD) for support.
  • The University of Florida focuses on identifying extremely high-risk neonates before surgery, using preemptive sVAD support to prepare them for potential cardiac transplantation.
  • This strategy is associated with low operative mortality rates (2.9%) after the first stage of surgery and high one-year survival rates (91.1%) for patients with hypoplastic left heart syndrome.
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Objectives: We reviewed outcomes in all 36 consecutive children <5 kg supported with the Berlin Heart pulsatile ventricular assist device (VAD) at the University of Florida, comparing those with univentricular circulation (n  =  23) to those with biventricular circulation (n  =  13).

Methods: The primary outcome was mortality. Kaplan-Meier methods and log-rank tests were used to assess group differences in long-term survival after VAD insertion.

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Introduction: Drysuits use flexible neck and wrist seals to maintain water-tight seals. However, if the seals exert too much pressure adverse physiological effects are possible, including dizziness, lightheadedness, syncope, and paresthesias in the hands. We aimed to quantify the seal pressures of neck and wrist seals in non-immersed divers.

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Some neonates with functionally univentricular hearts are at extremely high risk for conventional surgical palliation. Primary cardiac transplantation offers the best option for survival of these challenging neonates; however, waitlist mortality must be minimized. We have developed a comprehensive strategy for the management of neonates with functionally univentricular hearts that includes the selective use of conventional neonatal palliation in standard-risk neonates, hybrid approaches in neonates with elevated risk secondary to a noncardiac etiology, and neonatal palliation combined with insertion of a single ventricular assist device (VAD) in neonates with elevated risk secondary to a cardiac etiology.

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We reviewed outcomes in 82 consecutive children supported with the Berlin Heart pulsatile ventricular assist device (VAD), comparing those with functionally univentricular circulation (n = 34) to those with biventricular circulation (n = 48). The primary outcome was mortality. Kaplan-Meier (KM) methods and log-rank tests were used to assess group differences in long-term survival.

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Article Synopsis
  • - Patients with hypoplastic left heart syndrome (HLHS) have high risks during Norwood palliation, prompting a specialized management strategy to improve survival and heart donor usage; this study reviews outcomes of 83 neonates and infants treated from 2015 to 2021.
  • - Standard-risk patients primarily received Norwood palliation, while high-risk patients were treated with a Hybrid Stage 1 approach—some combined with ventricular assist devices (VAD)—to optimize their chances for eventual heart transplantation.
  • - The one-year survival rate was 90.4%; most standard-risk patients survived and progressed to further surgical stages, while a significant number of high-risk patients also successfully transitioned to transplantation, underscoring the effectiveness of this comprehensive management
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Nowhere is redundancy more indispensable than extended range cave diving. Training and practice in this discipline ensure divers are equipped with backup regulators, gauges, lights, and adequate breathing gas for a safe exit, emergencies, and decompression. Depending on penetration distances and depth, open circuit cave diving may require carrying more gas cylinders than can be logistically managed by the diver themselves while maintaining safe gas supply margins.

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Middle ear barotrauma is the most common diving-related injury. It is estimated to occur in more than 50% of experienced divers. Although divers learn how to effectively equalize their ears with various maneuvers, airway congestion may impede the ability to equalize the middle ear space via the Eustachian tube.

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• A patient presented with symptoms of heart failure and severe mitral regurgitation. • On postbypass imaging after MVR a small paravalvular leak appeared to be present. • Color flow originated from an unroofed CS with predominantly right-to-left shunting.

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We present a four-year-old female with an incidental finding of a congenital left atrial appendage aneurysm who underwent surgical resection with excellent results. This case highlights the importance of multimodal imaging in the diagnosis and characterization of this rare condition.

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Accurate monitoring of glucose in the perioperative environment has become increasingly important over the last few years. Because of increased cost, turnaround time, and sample volume, the use of central laboratory devices for glucose measurement has been somewhat supplanted by point-of-care (POC) glucose devices. The trade-off in moving to these POC systems has been a reduction in accuracy, especially in the hypoglycemic range.

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Abnormalities of blood glucose are common in patients undergoing surgery, and in recent years there has been considerable interest in tight control of glucose in the perioperative period. Implementation of any regime of close glycemic control requires more frequent measurement of blood glucose, a function for which small, inexpensive, and rapidly responding point-of-care devices might seem highly suitable. However, what is not well understood by many anesthesiologists and other staff caring for patients in the perioperative period is the lack of accuracy of home glucose meters that were designed for self-monitoring of blood glucose by patients.

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