Publications by authors named "Andrew P C McLean-Tooke"
Muscular polyarteritis nodosa where disease is isolated to skeletal muscle is a rare and often poorly recognised clinical entity. Patients typically present with fever and severe muscle pain limiting ability to ambulate without rise in creatine kinase. Often there is a significant delay between presentation and diagnosis, which requires histological confirmation.
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- * An 18-year-old male diagnosed with X-linked CGD initially presented with symptoms that resembled sarcoidosis and was treated with corticosteroids, but later developed pneumonia from Burkholderia cepacia complex, confirming his CGD diagnosis.
- * The study highlights the recognition of milder forms of CGD and emphasizes that CGD should be considered in patients of any age presenting with granulomatous diseases, particularly if they have a history of unusual or recurrent infections.
Adrenaline (epinephrine) is the recommended first line treatment for patients with anaphylaxis. This review discusses the safety and efficacy of adrenaline in the treatment of anaphylaxis in the light of currently available evidence. A pragmatic approach to use of adrenaline auto-injectors is suggested.
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