Publications by authors named "Andrew Kleven"

Background: There have been efforts to reduce adverse events and unplanned readmissions after total joint arthroplasty. The Rothman Index (RI) is a real-time, composite measure of medical acuity for hospitalized patients. We aimed to examine the association among in-hospital RI scores and complications, readmissions, and discharge location after total knee arthroplasty (TKA).

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Background: Elevated body mass index (BMI) is a risk factor for adverse outcomes following total hip arthroplasty (THA). It is unknown if preoperative weight loss to a BMI <40 kg/m is associated with reduced risk of adverse outcomes.

Methods: We retrospectively reviewed elective, primary THA performed at an academic center from 2015 to 2019.

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Background: Identifying risk factors for adverse outcomes and increased costs following total joint arthroplasty (TJA) is needed to ensure quality. The interaction between pre-operative healthcare utilization (pre-HU) and outcomes following TJA has not been fully characterized.

Methods: This is a retrospective cohort study of patients undergoing elective, primary total hip arthroplasty (THA, N = 1785) or total knee arthroplasty (TKA, N = 2159) between 2015 and 2019 at a single institution.

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Case: A 12-year-old girl presented with a both-bone forearm fracture after a fall. Fracture healing occurred, but nerve injury was not addressed until 18 months after injury. Magnetic resonance imaging and electromyography yielded a median nerve injury, and she underwent nerve reconstruction with sural nerve grafting.

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Objective: To compare patient outcomes following acute rehabilitation after total hip arthroplasty (THA) of two groups: patients treated by student physical therapists (SPTs) under licensed physical therapist (PT) supervision and by licensed PTs.

Participants: Seventy-eight patients with rehabilitation managed by supervised SPTs and 78 treated by licensed PTs. Inclusion criteria were admission between 2010 and 2014, first-time THA, age 55 to 70 yrs, and research consent.

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Here we show that the interplay between exercise training and dietary fat regulates myelinogenesis in the adult central nervous system. Mice consuming high fat with coordinate voluntary running wheel exercise for 7weeks showed increases in the abundance of the major myelin membrane proteins, proteolipid (PLP) and myelin basic protein (MBP), in the lumbosacral spinal cord. Expression of MBP and PLP RNA, as well that for Myrf1, a transcription factor driving oligodendrocyte differentiation were also differentially increased under each condition.

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