Publications by authors named "Andrew K Poznikoff"
Background: Anesthesiologists require an understanding of their patients' outcomes to evaluate their performance and improve their practice. Traditionally, anesthesiologists had limited information about their surgical outpatients' outcomes due to minimal contact post discharge. Leveraging digital health innovations for analyzing personal and population outcomes may improve perioperative care.
View Article and Find Full Text PDFBackground: Approaches to pediatric induction of anesthesia vary widely. While oral sedative premedication and inhalational induction are common, total intravenous anesthesia is becoming increasingly popular. Total intravenous anesthesia without anxiolytic premedication, which is the most commonly used technique in our hospital, requires intravenous (IV) cannula placement in an awake child.
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- Dexmedetomidine, an α2-adrenergic agonist, was studied for its effects on blood glucose and potassium levels in children undergoing elective surgery, highlighting potential adverse effects not previously rigorously assessed in pediatric patients.
- In a randomized controlled trial with 64 children, it was found that glucose levels increased significantly at 15 minutes post-administration, but this effect was minimal at 30 minutes, while potassium levels decreased slightly but were not significantly affected by the drug.
- The results suggest that while dexmedetomidine can elevate glucose levels, its impact on potassium levels is minor, indicating a need for careful monitoring of these parameters during pediatric anesthesia.
Background: Dexmedetomidine is a highly selective α2-adrenergic agonist, which is increasingly used in pediatric anesthesia and intensive care. Potential adverse effects that have not been rigorously evaluated in children include its effects on myocardial repolarization, which is important given that the drug is listed as a possible risk factor for torsades de pointes. We investigated the effect of 3 different doses of dexmedetomidine on myocardial repolarization and transmural dispersion in children undergoing elective surgery with total IV anesthesia.
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