Sessile serrated polyps at screening colonoscopy: have they been under diagnosed?

Objectives: The sessile serrated adenoma/polyp (SSA/P) is increasingly recognized as an important precursor to colorectal cancer (CRC) and may contribute to proximal postcolonoscopy CRCs. Hyperplastic polyps (HPs) generally follow a more benign course than do SSA/Ps, but they have a similar histologic appearance. Our aims were to identify patient and polyp factors associated with reclassification of HPs as SSA/Ps during a central pathology review and to characterize and compare their subsequent clinical management with other polyps.

Complex mucinous cystadenoma of undetermined malignant potential of the urachus.

Urachal mucinous neoplasms are rare and include both villous adenomas and invasive adenocarcinomas. These mucinous tumours should be completely excised as they can demonstrate aggressive clinical behaviour, including the development of pseudomyxoma peritonei. We describe a 70-year-old woman who presented with a lower abdominal mass and received a diagnosis of a rare, complex urachal mucinous cystadenoma of undetermined malignant potential.

Primary cardiac lymphoma: molecular cytogenetic characterization of a rare entity.

Background: The majority of cardiac atrial neoplasms represent benign myxomas. Rarely, malignant cardiac neoplasms are encountered and can include primary cardiac neoplasms, as well as secondary tumors involving the heart. As many cardiac neoplasms lack pathognomonic clinical features, histopathologic diagnosis is crucial for classification and appropriate treatment of these neoplasms.