Publications by authors named "Andrew J Lonie"

Article Synopsis
  • Australia faces unique challenges in upskilling biologists in bioinformatics due to its vast size and dispersed population.
  • A "hybrid" training approach was developed, combining experienced guidance with online webinars and in-person practical exercises, to effectively train researchers.
  • Since 2017, this method has successfully trained over 800 researchers in various bioinformatics topics and has proven adaptable for use in different locations and subjects.
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It is highly likely that successful pig-to-human xenotransplantation of vascularized organs will require genetic modification of the donor pig, and in particular of donor vascular endothelium. Promoters are generally tested in transgenic mice before generating transgenic pigs. Several promoters have been used to drive endothelial cell-specific expression in mice but none have yet been tested in pigs.

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