Publications by authors named "Andrew J Hayward"

Article Synopsis
  • This study examined how nerve injuries affect brain activity, specifically looking at hyperexcitability in the primary somatosensory cortex (S1) using a pig model.
  • Researchers recorded neuron activity with a multielectrode array to see how stimulating injured versus uninjured nerves changed brain responses.
  • The findings indicated that following nerve injury, there was a significant increase in excitability, particularly in cortical layer III, highlighting its key role in brain activity changes post-injury.
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Article Synopsis
  • The study analyzed how rats' licking behavior changed based on different concentrations of sucrose solutions, using traditional and new testing methods.
  • Results showed that when rats licked lower concentrations of sucrose alongside a higher concentration, they consumed more (positive contrast), while the opposite was true when consuming lower concentrations with lower ones (negative contrast).
  • Additionally, changes in licking patterns, such as cluster size, correlated with the concentration of the sucrose solutions consumed, indicating that sensory mechanisms play a role in these contrast effects.
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Article Synopsis
  • The study investigated conditioned taste aversions (CTA) to saccharin using three different methods: lithium chloride, amphetamine, and wheel running, analyzing licking patterns to assess taste palatability.
  • Pairing saccharin with amphetamine decreased its intake but did not alter licking behavior parameters (like cluster size or lick rate), suggesting no change in palatability.
  • In contrast, pairing saccharin with lithium or wheel running not only reduced intake but also affected licking behavior, indicating that these conditions caused a perception of nausea associated with the taste, whereas amphetamine did not.
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Synopsis of recent research by authors named "Andrew J Hayward"

  • - Andrew J Hayward's research encompasses the examination of neural excitability and behavioral responses using various experimental models, particularly focusing on somatosensory systems and taste aversion learning.
  • - Recent findings from his 2024 study on spared ulnar nerve injury highlighted increased hyperexcitability in specific cortical layers of the somatosensory cortex, particularly when comparing recordings from injured versus uninjured tissues in pigs.
  • - Earlier studies, including investigations into conditioned taste aversions, revealed differences in palatability responses based on the conditioning agent used, showing a nuanced aspect of how sensory experiences are modified by prior exposures.