Computational design of a self-assembling β-peptide oligomer.

The first computationally designed self-assembling oligomer consisting of exclusively β-amino acids (βAAs) is presented. The packing of a β-3(14) helix into coiled-coils of varying stoichiometries as a function of amino acid sequence is examined. β-Peptides with hVal repeating every third residue in the sequence appeared to have a strong propensity to pack into hexameric bundles.

Thirty-site P300 scalp distribution, amplitude variance across sites, and amplitude in detection of deceptive concealment of multiple guilty items.

Previous tests of P300 in deception detection have focused mainly on amplitude analysis. Since countermeasures for such tests have been reported, we looked here at other possible variables as deception indices: P300 scalp distribution and amplitude variance, both across 30 sites. We were also concerned, for the first time, in testing for recognition of more than one guilty item in a mock crime scenario.

Facial skin surface temperature changes during a "concealed information" test.

When individuals who commit a crime are questioned, they often show involuntary physiological responses to remembered details of that crime. This phenomenon is the basis for the concealed information test, in which rarely occurring crime-related details are embedded in a series of more frequently occurring crime-irrelevant items while respiratory, cardiovascular, and electrodermal responses are recorded. Two experiments were completed to investigate the feasibility of using facial skin surface temperature (SST) measures recorded using high definition thermographic images as the physiological measure during a concealed information test.

Comparison of polygraph data obtained from individuals involved in mock crimes and actual criminal investigations.

In a preliminary attempt to determine the generalizability of data from laboratory mock-crime studies, the authors examined the similarities and differences among the cardiovascular, electrodermal, and respiration responses of deceptive and nondeceptive individuals elicited to crime-relevant and crime-irrelevant questions. Participants in the laboratory group were randomly assigned to nondeceptive (n = 28) or deceptive (n = 27) treatment groups, and a mock-crime scenario was used. The field participants were confirmed nondeceptive (n = 28) or deceptive (n = 39) criminal suspects who underwent polygraph examinations between 1993 and 1997.