Spatiospectral brain networks reflective of improvisational experience.

Musical improvisers are trained to categorize certain musical structures into functional classes, which is thought to facilitate improvisation. Using a novel auditory oddball paradigm (Goldman et al., 2020) which enables us to disassociate a deviant (i.

Chlorthalidone: the forgotten diuretic.

Chlorthalidone's safety and efficacy in the management of hypertension has been demonstrated in landmark trials. Despite understanding the effects of thiazides on urinary sodium excretion and intravascular volume, the exact mechanism of their antihypertensive effects is not clearly understood. Common compensatory mechanisms for decreases in circulating plasma volume include increased adrenergic tone and systemic vascular resistance, as well as increases in the renin-angiotensin-aldosterone system.

Blind or deaf? A matter of aesthetics.

Blind or deaf? Surprisingly, a small but noticeable minority, 17%, opted for blindness. Another 6% were indifferent. For these individuals (23% of the sample), the loss of the aesthetic experience--music--was given relatively greater weight than the loss of the practical--conversation.

Clinical assessment of pediatric obstructive sleep apnea.

Objective: To determine whether children with a clinical assessment suggestive of obstructive sleep apnea (OSA) but with negative polysomnography (PSG) have improvement in their clinical assessment score after tonsillectomy and adenoidectomy (T&A) as compared with similar children who do not undergo surgery.

Methods: In a prospective, randomized, investigator-blinded, controlled trial, 59 otherwise healthy children (mean age: 6.3 years [3.