Publications by authors named "Andrew Glenn Demaine"
J Mol Med (Berl)
December 2006
Article Synopsis
- Keratin 8 (KRT8) is a key protein in the gastrointestinal tract, with studies showing that its overexpression can lead to pancreatic issues in mice, resembling conditions seen in chronic pancreatitis.
- Researchers investigated two specific KRT8 polymorphisms (Y54H and G62C) in a large patient cohort with pancreatic disorders across multiple countries, including a control group.
- Findings indicate that these KRT8 polymorphisms do not appear to increase the risk of developing pancreatitis or pancreatic cancer, as the frequencies of these variations were not significantly different between patients and control subjects.
