Disinfection of flexible fiberoptic laryngoscopes after in vitro contamination with Staphylococcus aureus and Candida albicans.

Objective: To determine the efficacy of various cleaning and disinfective methods in reducing bacterial and fungal load on flexible fiberoptic laryngoscopes (FFLs).

Design: In vitro model.

Subjects: Flexible fiberoptic laryngoscopes contaminated with Staphylococcus aureus and Candida albicans.

Effect of topical dexamethasone versus rimexolone on middle ear inflammation in experimental otitis media with effusion.

Conclusion: The lipopolysaccharide (LPS)-induced chinchilla otitis media (OM) model was proven useful in screening anti-inflammatory agents for topical use. Both 1% rimexolone and 1% dexamethasone are effective in reducing the volume of middle ear effusion and mucosal thickness compared with control groups. Topical corticosteroid therapy was efficacious in reducing middle ear mucosal inflammation.