Publications by authors named "Andrew Ebelhar"
An adenoid cystic carcinoma (AdCC) of the ceruminous glands is very rare; its diagnosis is most often challenging, and simple biopsies may be misleading. Our paper describes a case of a circumferential mass of the left ear canal that was initially reported as a basal cell carcinoma on biopsies in the clinic and on frozen sections intraoperatively. The final pathology was an AdCC of the ceruminous glands of the external auditory canal.
View Article and Find Full Text PDFArticle Synopsis
- - Perineural invasion (PNI) and lymphovascular invasion (LVI) are factors that negatively impact survival in patients undergoing salvage laryngectomy for laryngeal cancer.
- - A study of 78 patients found that PNI was present in 61.54%, and it was linked to a median overall survival of only 32 months, with a significant hazard ratio of 2.69.
- - The research concluded that PNI, LVI, and other factors like nodal disease and extracapsular spread greatly reduce survival chances for these patients.
Article Synopsis
- Antiterminator RNA enhances transcription elongation by altering the transcription complex, allowing it to terminate less frequently at specific terminators.
- The discovery of these RNAs originated from bacteriophage HK022, where they play a role in maximizing gene expression during viral infection.
- Research identified eight antiterminator RNA sequences, showing strong conservation in critical structural features, with notable variation in the HK639 bacteriophage's antiterminator RNA that includes a unique structure and sensitivity to changes in RNA polymerase's β' subunit.
Introduction: Although patients with pancreatic ductal adenocarcinoma (PDAC) frequently require medications to treat pre-existing conditions, the impact of these treatments on outcomes post-resection is unknown. The purpose of this study was to determine the impact of preoperative medications on overall survival after pancreatic resection.
Methods: Multi-institutional data on preoperative medications and outcomes in patients undergoing resection for PDAC were analyzed.