Management of Keratoacanthoma: 157 Tumors Treated With Surgery or Intralesional Methotrexate.

Background: Keratoacanthomas (KAs) are common tumors of squamous cell origin that grow rapidly and may regress; however, differentiation from an aggressive squamous cell carcinoma is problematic.

Objective: To report the authors' experience in managing KA with intralesional methotrexate (MTX) or surgical excision.

Materials And Methods: The authors collected data on 157 tumors (136 patients) over 6 months from a single institution.