Application of near-infrared spectroscopy to the determination of the sites of manufacture of proprietary products.

Reflectance near-infrared (NIR) spectroscopy has been investigated as a method to distinguish between the sites of manufacture of a number of proprietary tablets. As test samples, parallel imports which are pharmaceutically equivalent products manufactured at different sites have been used. Three products: Aremis/Besitran, Renitec and Voltarol Retard originating from two or more sites and Adalat from a single site were examined.