Publications by authors named "Andrew C Barton"

This paper describes the development and characterization of a label-less immunosensor for neuron-specific enolase (NSE) and its interrogation using an ac impedance protocol. Commercial screen-printed carbon electrodes were used as the basis for the sensor. Poly(1,2-diaminobenzene) was electrodeposited onto the sensors--and this modified surface was then sonochemically ablated to form an array of micropores.

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This paper describes the development and characterisation of labeless immunosensors for (a) the cardiac drug digoxin and (b) bovine serum albumin (BSA). Commercial screen-printed carbon electrodes were used as the basis for the sensors. Two methods were used to immobilise antibodies at the electrode surface.

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This paper describes the development of labeless immunosensors for the prostate cancer marker prostate specific antigen (PSA). Poly(1,2-diaminobenzene) was electrodeposited onto screen-printed carbon electrodes, and this modified surface was sonochemically ablated to form a microelectrode array. Polyaniline was electropolymerized within these pores to form a microarray of conductive polyaniline protrusions.

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A novel and patented procedure is described for the sonochemical fabrication of a new class of microelectrode array based sensor with electrode element populations of up to 2 x 10(5) cm(-2). For some years it has been accepted that microelectrode arrays offer an attractive route for lowering minimum limits of detection and imparting stir (convectional mass transport) independence to sensor responses; despite this no commercial biosensors, to date, have employed microelectrode arrays, largely due to the cost of conventional fabrication routes that have not proved commercially viable for disposable devices. Biosensors formed by our sonochemical approach offer unrivalled sensitivity and impart stir independence to sensor responses.

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