Publications by authors named "Andrew B Adrian"

A revisionary study revealed two species of monogeneans, Dactylogyrus crucis Rogers, 1967 and Dactylogyrus lythruri sp. n., parasitising Lythrurus Jordan (formerly a subgenus of Notropis Rafinesque, 1818).

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In all eukaryotic species examined, meiotic recombination, and crossovers in particular, occur non-randomly along chromosomes. The cause for this non-random distribution remains poorly understood but some specific DNA sequence motifs have been shown to be enriched near crossover hotspots in a number of species. We present analyses using machine learning algorithms to investigate whether DNA motif distribution across the genome can be used to predict crossover variation in Drosophila melanogaster, a species without hotspots.

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Background: Evidence in yeast indicates that gene expression is correlated with recombination activity and double-strand break (DSB) formation in some hotspots. Studies of nucleosome occupancy in yeast and mice also suggest that open chromatin influences the formation of DSBs. In Drosophila melanogaster, high-resolution recombination maps show an excess of DSBs within annotated transcripts relative to intergenic sequences.

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