Intramolecular C(sp)-C (sp) bond formation between phenanthroline and β-diketone thiosemicarbazones in Pt complexes: crystal structures and computational studies.

[PtCl(phen)] reacts with thiosemicarbazones derived from β-diketones (HL) leading to an intramolecular C-C coupling between phen and the ketone upon formation of tetradentate N,N,N,S chelates [Pt(Lphen)]. The reactions proceed via bidentate coordination of the doubly deprotonated (L) followed by an intra-nucleophilic attack and consecutive C-C bond formation.

Gold(III) complexes with ONS-Tridentate thiosemicarbazones: Toward selective trypanocidal drugs.

Tridentate thiosemicarbazone ligands with an ONS donor set, H2L(R) (R = Me and Et) were prepared by reactions of 1-phenyl-1,3-butanedione with 4-R-3-thiosemicarbazides. H2L(R) reacts with Na[AuCl4]·2H2O in MeOH in a 1:1 M ratio under formation of green gold(III) complexes of composition [AuCl(L(R))]. These compounds represent the first examples of gold(III) complexes with ONS chelate-bonded thiosemicarbazones.