Publications by authors named "Andressa Leite Di Domenico"
Clin Exp Immunol
January 2025
Article Synopsis
- * Behavioral tests showed that both PIL and vit-D led to depressive and anxious behaviors, along with cognitive impairments, but vit-D reduced harmful IgM and IgG deposits in the brain after 6 months.
- * The findings suggest that the PIL model effectively represents systemic lupus erythematosus (SLE) with neuropsychiatric manifestations, indicating vit-D's potential for reducing brain inflammation while improving memory without affecting anxiety or depression.
Adv Rheumatol
January 2024
Article Synopsis
- Systemic lupus erythematosus (SLE) is an autoimmune disease that can impact various organs, leading to complications like neuropsychiatric lupus (NPSLE).
- Research indicates a link between SLE/NPSLE and vitamin D deficiency, which can contribute to cognitive issues and reduced blood flow in the brain.
- The review article focuses on how vitamin D levels and supplementation relate to neuropsychiatric symptoms in both human patients and animal models of NPSLE.
